Van de Ven Double Halts Everton's Run at New Stadium
Micky van de Ven became the initial defender to net twice in a Premier League match for Spurs since Jan Vertonghen in March 2013.
Match summary
The Spurs defender heads home two times in opening period
Everton's defender has goal ruled after video check
Pape Matar Sarr nets third in 89th minute
This loss is Everton's first at Hill Dickinson Stadium
Micky van de Ven found the net twice as Tottenham prolonged their unbeaten run on the road in the top division and handed Everton their first defeat at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having departed their historic home behind after more than a century at the end of last season.
But Tottenham's leader Van de Ven pounced twice from corners in the opening 45 minutes to place their strong form at jeopardy, and they were failed to turn it around before the midfielder - set up by ex-Everton forward Richarlison - nodded in a third to seal the victory.
Jake O'Brien believed he had levelled the tally five minutes after Van de Ven's first goal, glancing a powerful header past the Spurs keeper from an set-piece.
The Portuguese striker, meanwhile, missed a number of opportunities, while the Italian goalkeeper made a series of fine stops to ensure the London club went five matches on the road without defeat in the Premier League.
But the video assistant referee stepped in, advising Craig Pawson to check the goal on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had impeded with the Spurs keeper.
This victory moves Thomas Frank's team into third place in the Premier League, a handful of points off north London rivals and table-toppers the Gunners.
Everton stay 14th and are half a dozen points clear of the drop zone.
Spurs breakdown: The defender fulfils role at each end of pitch
Following a uninspiring weekday display in the Champions League against Monaco, where they mustered a only two shots on target, the manager chose Randal Kolo Muani in attack instead of ex-Everton forward the Brazilian.
The summer signing was unable to influence the game before being replaced for the substitute after an hour on the field, but it turns out he proved unnecessary in the end.
Defender the Dutchman transformed into an attacking force to be feared.
Tottenham's first goal came from a well-worked set-piece play, with the midfielder heading the ball toward the face of goal for an unmarked Van de Ven to head home.
And Ven de Ven - stepping up as skipper in Cristian Romero's unavailability - notched his second in first-half stoppage time as he rose above the England keeper to nod in.
Van de Ven was equally outstanding in defence, partnering effectively with his defensive colleague as the pair dealt excellently with the numerous deliveries thrown their way by the opposition.
Everton analysis: Everton lacking striker's instinct
Everton's new home had been a happy hunting ground, but it appears the freshness may have worn off somewhat and supporters flocked to the gates after Sarr's final goal for Tottenham.
The break in the team's winning streak at home will not be a massive worry for the manager, but their attacking woes are.
Beto and the other striker - the Toffees' two established centre-forwards - had scored only one league goal between them before Sunday's match.
And they were unable to add to that miserable tally on a damp and dreary night on Merseyside.
The striker's performance was summed up when he chose to overhead kick a clear chance from close range, even with having room and time to readjust for a more conventional attempt that would have challenged the keeper.
The substitute, too, was unable to make an impact after replacing Beto in the 65th minute.
It wasn't for a shortage of opportunity. Most of the home side's attacks came through Grealish and Ndiaye, who relentlessly delivered threatening balls into the Spurs box.
What next for these two sides?
Everton: Moyes' men head to the Stadium of Light in the top flight on Monday, 3 November at 20:00 GMT.
Spurs: The London club go to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup tie against Newcastle.